The field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. The increasing availability of large genomic data sets requires powerful statistical methods to analyse and interpret them, ge...
The field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. The increasing availability of large genomic data sets requires powerful statistical methods to analyse and interpret them, generating both computational and conceptual challenges for the field. Computational Molecular Evolution provides an up-to-date and comprehensive coverage of modern statistical and computational methods used in molecular evolutionary analysis, such as maximum likelihood and Bayesian statistics. Yang describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes. The book emphasizes essential concepts rather than mathematical proofs. It includes detailed derivations and implementation details, as well as numerous illustrations, worked examples, and exercises.It will be of relevance and use to students and professional researchers (both empiricists and theoreticians) in the fields of molecular phylogenetics, evolutionary biology, population genetics, mathematics, statistics and computer science. Biologists who have used phylogenetic software programs to analyze their own data will find the book particularly rewarding, although it should appeal to anyone seeking an authoritative overview of this exciting area of computational biology.
作者简介
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杨子恒,1964年生于甘肃通渭,1984年毕业于甘肃农业大学,1992年获北京农业大学博士学位。曾在甘肃农业大学和北京农业大学畜牧系工作以及英美等国从事博士后研究。1997年起在伦敦大学学院(University College London)生物系任教(1997-2000年任讲师,2000-72001年任副教授,2001年后任教授),2006年当选为英国皇家学会院士(Fellow of the Royal Society)。
作为国际知名的统计进化生物学家,杨子恒博士一直致力于发展新的最大似然模型及计算机程序(PAML),1993年起在国际学术刊物发表论文100余篇;学术兼职包括Genetics、MoIecular Biology and Evolution、Journal of Molecular Evolution和Systematic Bio...
杨子恒,1964年生于甘肃通渭,1984年毕业于甘肃农业大学,1992年获北京农业大学博士学位。曾在甘肃农业大学和北京农业大学畜牧系工作以及英美等国从事博士后研究。1997年起在伦敦大学学院(University College London)生物系任教(1997-2000年任讲师,2000-72001年任副教授,2001年后任教授),2006年当选为英国皇家学会院士(Fellow of the Royal Society)。
作为国际知名的统计进化生物学家,杨子恒博士一直致力于发展新的最大似然模型及计算机程序(PAML),1993年起在国际学术刊物发表论文100余篇;学术兼职包括Genetics、MoIecular Biology and Evolution、Journal of Molecular Evolution和Systematic Biology等刊物副主编。
本书需要耐心的仔细品看,因为有些内容还是满学术的。
讲的特别好
需要静下心慢慢看
许多都超出了我的认知